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Long-term use also causes changes in other brain chemical systems and circuits as well, affecting functions that include: learning, judgment, decision-making, stress, memory, behavior. Despite being aware of these harmful outcomes, many people who use drugs continue to take them, which is the nature of addiction.
Why do some people get addicted to drugs, while others don't have a problem with it? It is impossible to predict if someone will become addicted to drugs. A variety of factors can influence the risk of developing addiction. A person is more at risk for addiction if they have more risk factors.